IV.3. Bioreactors in tissue engineering.
نویسندگان
چکیده
منابع مشابه
Bioreactor Systems for Human Bone Tissue Engineering
Critical size skeletal defects resulting from trauma and pathological disorders still remain a major clinical problem worldwide. Bone engineering aims at generating unlimited amounts of viable tissue substitutes by interfacing osteocompetent cells of different origin and developmental stage with compliant biomaterial scaffolds, and culture the cell/scaffold constructs under proper culture condi...
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Tissue engineering involves using the principles of biology, chemistry and engineering to design a 'neotissue' that augments a malfunctioning in vivo tissue. The main requirements for functional engineered tissue include reparative cellular components that proliferate on a biocompatible scaffold grown within a bioreactor that provides specific biochemical and physical signals to regulate cell d...
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A bioreactor can be defined as a device that uses mechanical means to influence biological processes. In tissue engineering bioreactors can be used to aid in the in vitro development of new tissue by providing biochemical and physical regulatory signals to cells and encouraging them to undergo differentiation and/or to produce extracellular matrix prior to in vivo implantation. This chapter dis...
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The low-shear, microgravity-simulating cell culture environment in Rotating Wall Vessel (RWV) Bioreactors RWV Bioreactors is well suited for generating differentiated 3-D tissue constructs (organoids). Biochemical, immunological and molecular biological techniques, including cDNA arrays, were used to analyze signal transduction, catecholamine contents, and gene expression in 3-D tissue-like con...
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Cardiovascular disease is the leading cause of morbidity and mortality in the Western World. The inability of fully differentiated, load-bearing cardiovascular tissues to in vivo regenerate and the limitations of the current treatment therapies greatly motivate the efforts of cardiovascular tissue engineering to become an effective clinical strategy for injured heart and vessels. For the effect...
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عنوان ژورنال:
- Studies in health technology and informatics
دوره 152 شماره
صفحات -
تاریخ انتشار 2010